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High costs of development and intellectual property issues may limit access to senolytic therapies for wider populations.126 Need for More Clinical Trials: While preclinical data are promising, large-scale, long-term clinical trials are needed to evaluate efficacy, safety, and optimal dosing of senolytics in humans

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Consuming 2.6 micrograms (mcg) of vitamin B12 daily is sufficient for adult males to meet their needs